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    Monitoring metabolic energy expenditure, health, and fitness with a breath analyzer

    Original @ MIT News – Bioengineering and biotechnology Simple-to-use, low-cost respiratory sensor enables measurement and tracking of personal metabolism. [...]

    Diffusion dynamics play an essential role in regulating stem cells and tissue development

    Original @ – latest science and technology news stories Gradients of molecular signaling factors play an essential role in numerous events in embryonic development, from patterning limb and organ formation to the intricate shaping of the brain and neuroanatomical architecture. These gradients are a consequence of diffusion dynamics in tissues, and newly published work describes two vital aspects of these diffusion processes in tissue development—first, the influence of molecular diffusion gradients on stem cell signaling pathways is described in detail, including a summary of recent discoveries in how gas and nutrient concentrations can influence stem cell potency, differentiation, and metabolism. Secondly, the paper describes novel applications of diffusion equations to model concentration gradients of nutrients and signaling factors in three-dimensional (3D) tissue constructs under a variety of conditions, including with or without cellular metabolism of the diffusing substance. [...]

    How physical exercise prevents dementia

    Original @ Medical Xpress – latest medical and health news stories Numerous studies have shown that physical exercise seems beneficial in the prevention of cognitive impairment and dementia in old age. Now researchers at Goethe University Frankfurt have explored in one of the first studies worldwide how exercise affec… [...]

    Scientists discover a new way to treat type 2 diabetes

    Original @ Medical Xpress – latest medical and health news stories Medication currently being used to treat obesity is also proving to have significant health benefits for patients with type 2 diabetes. A new study published today in Molecular Metabolism explains how this therapeutic benefit for type 2 diabetes is ach… [...]

    Engineered liver tissue expands after transplant

    Original @ MIT News – Health sciences and technology Tiny implantable “seeds” of tissue produce fully functional livers. [...]

    Testosterone prescribing in VA varies by provider’s age, experience, specialty and region

    Original @ Medical Xpress – latest medical and health news stories Providers in the Veterans Health Administration (VA) system vary in their testosterone prescribing practices, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. This is the first study to examine provider and site predictors of testosterone prescribing in the VA. [...]

    Clinical tests show that biosensors could pave the way for a personalized antibiotherapy in the future

    Original @ – latest science and technology news stories Personalized drug therapy adjusting the dose, dosage intervals, and the duration of treatment to fit individual patients’ needs is increasingly important. Frequently, medications are dosed in such a way that each patient receives the same standardized amount of a drug. Thus, clinical conditions such as overall state of health, metabolism, or other physical factors are often not sufficiently considered. A research team at the University of Freiburg has developed a bioanalytical method to measure the class of β-lactam antibiotics in human blood onsite – in the operating room, intensive ward or doctor’s office, or even the patient’s home. “This way, we can easily determine just how quickly the human body metabolizes a drug,” said the microsystems engineer Dr. Can Dincer, who is the head of the research team. [...]

    How social rank can trigger vulnerability to stress

    Original @ – latest science and technology news stories Stress is a major risk factor for a range of psychopathologies. However, stress does not affect everyone equally: in the face of sustained adversity, some people develop depression symptoms while others adapt and remain resilient. Identifying risk fact… [...]

    Machine-learning techniques unlock benefit of weight loss for type 2 diabetes patients

    Original @ Medical Xpress – latest medical and health news stories Losing weight reduces the risk of long-term cardiovascular illness and mortality for the majority of patients with type 2 diabetes, but for a small subgroup, weight-loss intervention can lead to dramatically worse outcomes, according to new research published today in The Lancet Diabetes & Endocrinology. [...]

    Targeting ‘broken’ metabolism in immune cells reduces inflammatory disease

    Original @ Medical Xpress – latest medical and health news stories The team, led by researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, believes the approach could offer new hope in the treatment of inflammatory conditions like arthritis, autoimmune diseases and sepsis. [...]